on Saturday through injury, adding to Zinedine Zidane’s defensive concerns.

Centre-back Varane limped off the pitch in the 38th minute of Madrid’s 3-2 Champions League victory over Borussia Dortmund on Wednesday with what appeared to be a muscular issue.

The loss of the 24-year-old for the visit of Eduardo Berizzo’s side, level with Madrid on 28 points in La Liga, is a bitter blow for Zidane, who will be without suspended trio Sergio Ramos, Dani Carvajal and Casemiro, with Jesus Vallejo injured.

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“The player is optimistic but he will not be available on Saturday, that’s for sure,” said Zidane, before admitting midfielder Marcos Llorente may have to slot into the back four.